Jerry Cantrell tunes to Drop D and uses a heavy, dark distortion tone. Mid-heavy and aggressive.
Signal Chain
Boss MT-2 Metal Zone→Marshall JCM800→4x12 V30→Output
PedalBoss MT-2 Metal Zone
bass
6
gain
7
mids
4
level
7
treble
6
AmpMarshall JCM800
bass
6
gain
6
mids
5
treble
6
presence
4
Cab / IR4x12 V30
micSM57
mic positioncenter cap
Notes
Drop D tuning. The heavy open D power chord riff is what defines this song.
Don't have Helix?
See the same signal chain mapped to another platform. Knob values carry over as starting points — gain ranges differ between platforms. NAM/TONEX users: the real gear names are what to search for as captures.