Muse
Bellamy created the repeating figure by playing simple power chords while a MIDI program switched Whammy octave states in rhythm. The guitar was split into multiple paths and processed through pitch shifters and synthesizers; Drop C reflects the established live recreation because the precise studio tuning remains uncertain. Source: Premier Guitar’s Matt Bellamy interview, MuseWiki’s Tones page and Manson Holoflake documentation.