Matt Bellamy uses a heavily processed, almost glitchy distortion. Whammy pedal and tight distortion define this riff.
Signal Chain
DigiTech Whammy→ProCo RAT→Diezel VH4→4x12 V30→Output
PedalDigiTech Whammy
mix
5
PedalProCo RAT
gain
7
level
7
filter5
AmpDiezel VH4
bass
5
gain
6
mids
6
treble
7
presence
5
Cab / IR4x12 V30
micSM57
mic positioncenter cap
Notes
The riff has a tight, percussive feel. Mute aggressively between notes for the choppy character.
Don't have Neural DSP?
See the same signal chain mapped to another platform. Knob values carry over as starting points — gain ranges differ between platforms. NAM/TONEX users: the real gear names are what to search for as captures.